Genetic evaluation finds hyperlink between obesity-related genes and rheumatoid arthritis

An evaluation of genetic information collected from greater than 850,000 people of European ancestry has discovered a hyperlink between obesity-related genes and rheumatoid arthritis.

Within the Arthritis & Rheumatology evaluation, investigators discovered an elevated threat of rheumatoid arthritis when physique mass index was predicted to be excessive primarily based on a person’s genetics. This was noticed for each women and men.

These outcomes spotlight an necessary function of weight problems within the pathological growth of rheumatoid arthritis, in addition to present a possible actionable preventive technique. Future research are wanted to grasp the organic mechanisms underlying such a hyperlink, and to grasp how weight problems might causally affect rheumatoid arthritis prognosis.”

Xia Jiang, PhD, Senior Creator, Karolinska Institute, Sweden


Journal reference:

Tang, B., et al. (2020) Weight problems‐associated traits and the event of rheumatoid arthritis – proof from genetic information. Arthritis & Rheumatology.

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