Systematic evaluation of epicardial adipose tissue in sufferers with obstructive sleep apnea

In a brand new publication from Cardiovascular Improvements and Functions, Bin Liu, Yingrui Li, Janlin Du, Qiang She and Songbai Deng from The Second Affiliated Hospital of Chongqing Medical College, Chongqing, China contemplate epicardial adipose tissue in sufferers with obstructive sleep apnea.

Obstructive sleep apnea (OSA) syndrome is a respiratory dysfunction characterised by repetitive episodes of higher airway obstruction brought on by partial or full collapse of the higher airway.

Epicardial adipose tissue (EAT) is a possible threat issue for obstructive sleep apnea (OSA). The authors of this text carried out a meta-analysis to evaluate the affiliation of EAT with OSA.

The authors assessed the affiliation of EAT thickness (EAT-t) and EAT quantity (EAT-v) with OSA by a meta-analysis. Ten research had been included within the last evaluation. In contrast with that in controls, EAT-t in OSA sufferers was considerably elevated (standardized imply distinction 0.88, 95% confidence interval 0.72-1.05, P=0.000).

Moreover, EAT-t was larger in OSA sufferers than in controls with comparable BMIs. Nevertheless, the authors didn’t discover important variations in EAT-v between OSA sufferers and controls (standardized imply distinction 2.46, 95% confidence interval −0.36 to five.29, P=0.088).

EAT-t within the delicate, reasonable, and extreme OSA subgroups was larger than within the controls. As well as, there have been important variations in EAT-t among the many delicate, reasonable, and extreme OSA subgroups.

EAT-t was larger in sufferers with OSA than in controls, and EAT-t was additionally related to the severity of OSA. These findings could present a brand new clue for the pathogenesis and remedy of OSA.


Journal reference:

Deng. S., et al. (2020) Epicardial Adipose Tissue in Sufferers with Obstructive Sleep Apnea: A Systematic Evaluation and Meta-analysis. Cardiovascular Improvements and Functions.

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